The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization

BACKGROUND: ESCRT-III proteins are involved in many membrane remodeling processes including multivesicular body biogenesis as first discovered in yeast. In humans, ESCRT-III CHMP2 exists as two isoforms, CHMP2A and CHMP2B, but their physical characteristics have not been compared yet. RESULTS: Here,...

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Udgivet i:BMC Biol
Main Authors: Alqabandi, Maryam, de Franceschi, Nicola, Maity, Sourav, Miguet, Nolwenn, Bally, Marta, Roos, Wouter H., Weissenhorn, Winfried, Bassereau, Patricia, Mangenot, Stéphanie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033747/
https://ncbi.nlm.nih.gov/pubmed/33832485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-00983-9
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