Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen

There is an urgent need to identify therapeutics for the treatment of Coronavirus disease 2019 (COVID-19). Although different antivirals are given for the clinical management of SARS-CoV-2 infection, their efficacy is still under evaluation. Here, we have screened existing drugs approved for human u...

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Publicat a:Front Pharmacol
Autors principals: Rodon, Jordi, Muñoz-Basagoiti, Jordana, Perez-Zsolt, Daniel, Noguera-Julian, Marc, Paredes, Roger, Mateu, Lourdes, Quiñones, Carles, Perez, Carles, Erkizia, Itziar, Blanco, Ignacio, Valencia, Alfonso, Guallar, Víctor, Carrillo, Jorge, Blanco, Julià, Segalés, Joaquim, Clotet, Bonaventura, Vergara-Alert, Júlia, Izquierdo-Useros, Nuria
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033486/
https://ncbi.nlm.nih.gov/pubmed/33841165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.646676
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