Conversion of Reactive Astrocytes to Induced Neurons Enhances Neuronal Repair and Functional Recovery After Ischemic Stroke

The master neuronal transcription factor NeuroD1 can directly reprogram astrocytes into induced neurons (iNeurons) after stroke. Using viral vectors to drive ectopic ND1 expression in gliotic astrocytes after brain injury presents an autologous form of cell therapy for neurodegenerative disease. Cul...

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Detaylı Bibliyografya
Yayımlandı:Front Aging Neurosci
Asıl Yazarlar: Jiang, Michael Qize, Yu, Shan Ping, Wei, Zheng Zachory, Zhong, Weiwei, Cao, Wenyuan, Gu, Xiaohuan, Wu, Anika, McCrary, Myles Randolph, Berglund, Ken, Wei, Ling
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032905/
https://ncbi.nlm.nih.gov/pubmed/33841125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.612856
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