Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is the most common malignant epithelial tumor in the oral cavity. Emerging evidence has demonstrated the important function roles of long noncoding RNAs (lncRNAs) in human cancers. LncRNA promoter of CDKN1A antisense DNA damage activated RNA (PANDAR) functions as...

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Detalles Bibliográficos
Publicado en:Front Mol Biosci
Autores principales: Jia, Tingting, Wang, Fengze, Qiao, Bo, Ren, Yipeng, Xing, Lejun, Zhang, Haizhong, Li, Hongbo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032867/
https://ncbi.nlm.nih.gov/pubmed/33842552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.653787
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