Genetic variants of programmed cell death 1 are associated with HBV infection and liver disease progression

The inhibitory effects of programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) modulates T-cell depletion. T-cell depletion is one of the key mechanisms of hepatitis B virus (HBV) persistence, in particular liver disease progression and the development of hepatocellular carcinoma (HCC...

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Udgivet i:Sci Rep
Main Authors: Hoan, Nghiem Xuan, Huyen, Pham Thi Minh, Binh, Mai Thanh, Trung, Ngo Tat, Giang, Dao Phuong, Linh, Bui Thuy, Dung, Dang Thi Ngoc, Pallerla, Srinivas Reddy, Kremsner, Peter G., Velavan, Thirumalaisamy P., Bang, Mai Hong, Song, Le Huu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032722/
https://ncbi.nlm.nih.gov/pubmed/33833369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87537-9
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