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Single molecule network analysis identifies structural changes to caveolae and scaffolds due to mutation of the caveolin-1 scaffolding domain

Caveolin-1 (CAV1), the caveolae coat protein, also associates with non-caveolar scaffold domains. Single molecule localization microscopy (SMLM) network analysis distinguishes caveolae and three scaffold domains, hemispherical S2 scaffolds and smaller S1B and S1A scaffolds. The caveolin scaffolding...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wong, Timothy H., Khater, Ismail M., Joshi, Bharat, Shahsavari, Mona, Hamarneh, Ghassan, Nabi, Ivan R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032680/
https://ncbi.nlm.nih.gov/pubmed/33833286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86770-6
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