Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood

The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure induces long-term changes in baseline responses to anxiety-inducing environments, and if so, whether its re-exposure in adulthood would ameliorate this anxiety-like phenotype. An additional goal was to assess the...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Flores-Ramirez, Francisco J., Themann, Anapaula, Sierra-Fonseca, Jorge A., Garcia-Carachure, Israel, Castillo, Samuel A., Rodriguez, Minerva, Lira, Omar, Preciado-Piña, Joshua, Warren, Brandon L., Robison, Alfred J., Iñiguez, Sergio D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032660/
https://ncbi.nlm.nih.gov/pubmed/33833356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87378-6
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