Low-Dose vs Standard-Dose Alteplase in Acute Lacunar Ischemic Stroke: The ENCHANTED Trial

OBJECTIVE: To determine any differential efficacy and safety of low- vs standard-dose IV alteplase for lacunar vs nonlacunar acute ischemic stroke (AIS), we performed post hoc analyzes from the Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED) alteplase dose arm. METHODS: In...

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Published in:Neurology
Main Authors: Zhou, Zien, Delcourt, Candice, Xia, Chao, Yoshimura, Sohei, Carcel, Cheryl, Torii-Yoshimura, Takako, You, Shoujiang, Malavera, Alejandra, Chen, Xiaoying, Hackett, Maree L., Woodward, Mark, Chalmers, John, Xu, Jianrong, Robinson, Thompson G., Parsons, Mark W., Demchuk, Andrew M., Lindley, Richard I., Mair, Grant, Wardlaw, Joanna M., Anderson, Craig S.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032382/
https://ncbi.nlm.nih.gov/pubmed/33536271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000011598
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