Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study

OBJECTIVE: To evaluate the effects of long-term tumor necrosis factor (TNF) inhibition on the risk and age at onset of Parkinson disease (PD), we performed a 2-sample Mendelian randomization study using genome-wide association studies (GWAS) summary statistics. METHODS: Genetic variants in the vicin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neurology
Auteurs principaux: Kang, Xiaoying, Ploner, Alexander, Pedersen, Nancy L., Bandres-Ciga, Sara, Noyce, Alastair J., Wirdefeldt, Karin, Williams, Dylan M.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2021
Sujets:
Null Hypothesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032365/
https://ncbi.nlm.nih.gov/pubmed/33608417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000011630
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