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Targeting MCL1 to induce mitophagy is a potential therapeutic strategy for Alzheimer disease

Mitochondrial dysfunction is associated with the occurrence of a variety of neurodegenerative diseases, especially Alzheimer disease (AD). As a mitochondrial quality control process, mitophagy is greatly inhibited in AD; increasing evidence shows that the induction of mitophagy is an effective thera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Cen, Xufeng, Xu, Xiaoyan, Xia, Hongguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032245/
https://ncbi.nlm.nih.gov/pubmed/33342330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1860542
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