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Machine Learning and Systems Biology Approaches to Characterize Dosage-Based Gene Dependencies in Cancer Cells

Mapping of cancer survivability factors allows for the identification of novel biological insights for drug targeting. Using genomic editing techniques, gene dependencies can be extracted in a high-throughput and quantitative manner. Dependencies have been predicted using machine learning techniques...

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Veröffentlicht in:J Bioinform Syst Biol
Hauptverfasser: Meng-Lin, Kevin, Ung, Choong Yong, Weiskittel, Taylor M, Chen, Alex, Zhang, Cheng, Correia, Cristina, Li, Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031731/
https://ncbi.nlm.nih.gov/pubmed/33842927
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