Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy

BACKGROUND: Some concomitant medications including antibiotics (ATB) have been reproducibly associated with worse survival following immune checkpoint inhibitors (ICIs) in unselected patients with non-small cell lung cancer (NSCLC) (according to programmed death-ligand 1 (PD-L1) expression and treat...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Cortellini, Alessio, Di Maio, Massimo, Nigro, Olga, Leonetti, Alessandro, Cortinovis, Diego L, Aerts, Joachim GJV, Guaitoli, Giorgia, Barbieri, Fausto, Giusti, Raffaele, Ferrara, Miriam G, Bria, Emilio, D'Argento, Ettore, Grossi, Francesco, Rijavec, Erika, Guida, Annalisa, Berardi, Rossana, Torniai, Mariangela, Sforza, Vincenzo, Genova, Carlo, Mazzoni, Francesca, Garassino, Marina Chiara, De Toma, Alessandro, Signorelli, Diego, Gelibter, Alain, Siringo, Marco, Marchetti, Paolo, Macerelli, Marianna, Rastelli, Francesca, Chiari, Rita, Rocco, Danilo, Della Gravara, Luigi, Inno, Alessandro, Michele, De Tursi, Grassadonia, Antonino, Di Marino, Pietro, Mansueto, Giovanni, Zoratto, Federica, Filetti, Marco, Santini, Daniele, Citarella, Fabrizio, Russano, Marco, Cantini, Luca, Tuzi, Alessandro, Bordi, Paola, Minuti, Gabriele, Landi, Lorenza, Ricciardi, Serena, Migliorino, Maria R, Passiglia, Francesco, Bironzo, Paolo, Metro, Giulio, Adamo, Vincenzo, Russo, Alessandro, Spinelli, Gian Paolo, Banna, Giuseppe L, Friedlaender, Alex, Addeo, Alfredo, Cannita, Katia, Ficorella, Corrado, Porzio, Giampiero, Pinato, David J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031700/
https://ncbi.nlm.nih.gov/pubmed/33827906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-002421
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