Solubilization and thermodynamic properties of simvastatin in various micellar solutions of different non-ionic surfactants: Computational modeling and solubilization capacity

The aim of this work was to solubilize simvastatin (SIM) using different micellar solutions of various non-ionic surfactants such as Tween-80 (T80), Tween-20 (T20), Myrj-52 (M52), Myrj-59 (M59), Brij-35 (B35) and Brij-58 (B58). The solubility of SIM in water (H(2)O) and different micellar concentrat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shakeel, Faiyaz, Alshehri, Sultan, Ibrahim, Mohamed A., Altamimi, Mohammad, Haq, Nazrul, Elzayat, Ehab M., Shazly, Gamal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031458/
https://ncbi.nlm.nih.gov/pubmed/33831070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249485
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