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Osteosarcoma Cell-Derived Small Extracellular Vesicles Enhance Osteoclastogenesis and Bone Resorption Through Transferring MicroRNA-19a-3p

Osteosarcoma (OS) is the most common primary bone cancer characterized by an aggressive phenotype with bone destruction. The prognosis of OS patients remains unoptimistic with the current treatment strategy. Recently, osteoclasts are believed to play a crucial role in cancer bone metastasis. Thus, o...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Luo, Tingting, Zhou, Xiaocheng, Jiang, Erhui, Wang, Lin, Ji, Yaoting, Shang, Zhengjun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029976/
https://ncbi.nlm.nih.gov/pubmed/33842319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618662
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