Genetic alterations related to BRAF‐FGFR genes and dysregulated MAPK/ERK/mTOR signaling in adult pilocytic astrocytoma

Pilocytic astrocytomas occur rarely in adults and show aggressive tumor behavior. However, their underlying molecular‐genetic events are largely uncharacterized. Hence, 59 adult pilocytic astrocytoma (APA) cases of classical histology were studied (MIB‐1 LI: 1%–5%). Analysis of BRAF alterations usin...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Pathak, Pankaj, Kumar, Anupam, Jha, Prerana, Purkait, Suvendu, Faruq, Mohammed, Suri, Ashish, Suri, Vaishali, Sharma, Mehar C., Sarkar, Chitra
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029314/
https://ncbi.nlm.nih.gov/pubmed/27608415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12444
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