Genetic alterations related to BRAF‐FGFR genes and dysregulated MAPK/ERK/mTOR signaling in adult pilocytic astrocytoma

Pilocytic astrocytomas occur rarely in adults and show aggressive tumor behavior. However, their underlying molecular‐genetic events are largely uncharacterized. Hence, 59 adult pilocytic astrocytoma (APA) cases of classical histology were studied (MIB‐1 LI: 1%–5%). Analysis of BRAF alterations usin...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Pathak, Pankaj, Kumar, Anupam, Jha, Prerana, Purkait, Suvendu, Faruq, Mohammed, Suri, Ashish, Suri, Vaishali, Sharma, Mehar C., Sarkar, Chitra
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029314/
https://ncbi.nlm.nih.gov/pubmed/27608415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12444
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