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Non‐neuronal Cells in ALS: Role of Glial, Immune cells and Blood‐CNS Barriers

Neurological dysfunction and motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is strongly associated with neuroinflammation reflected by activated microglia and astrocytes in the CNS. In ALS endogenous triggers in the CNS such as aggregated protein and misfolded proteins activate a p...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Puentes, Fabiola, Malaspina, Andrea, van Noort, Johannes M., Amor, Sandra
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029111/
https://ncbi.nlm.nih.gov/pubmed/26780491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12352
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