Accelerated Tau Aggregation, Apoptosis and Neurological Dysfunction Caused by Chronic Oral Administration of Aluminum in a Mouse Model of Tauopathies

To clarify whether long‐term oral ingestion of aluminum (Al) can increase tau aggregation in mammals, we examined the effects of oral Al administration on tau accumulation, apoptosis in the central nervous system (CNS) and motor function using tau transgenic (Tg) mice that show very slowly progressi...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Oshima, Etsuko, Ishihara, Takeshi, Yokota, Osamu, Nakashima‐Yasuda, Hanae, Nagao, Shigeto, Ikeda, Chikako, Naohara, Jun, Terada, Seishi, Uchitomi, Yosuke
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028981/
https://ncbi.nlm.nih.gov/pubmed/23574527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12059
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