Accelerated Tau Aggregation, Apoptosis and Neurological Dysfunction Caused by Chronic Oral Administration of Aluminum in a Mouse Model of Tauopathies

To clarify whether long‐term oral ingestion of aluminum (Al) can increase tau aggregation in mammals, we examined the effects of oral Al administration on tau accumulation, apoptosis in the central nervous system (CNS) and motor function using tau transgenic (Tg) mice that show very slowly progressi...

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Publicat a:Brain Pathol
Autors principals: Oshima, Etsuko, Ishihara, Takeshi, Yokota, Osamu, Nakashima‐Yasuda, Hanae, Nagao, Shigeto, Ikeda, Chikako, Naohara, Jun, Terada, Seishi, Uchitomi, Yosuke
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028981/
https://ncbi.nlm.nih.gov/pubmed/23574527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12059
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