Computational prediction of potential siRNA and human miRNA sequences to silence orf1ab associated genes for future therapeutics against SARS-CoV-2

The coronavirus disease 2019 (COVID-19) is an ongoing pandemic caused by an RNA virus termed as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 possesses an almost 30kbp long genome. The genome contains open-reading frame 1ab (ORF1ab) gene, the largest one of SARS-CoV-2, enc...

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Publicado no:Inform Med Unlocked
Main Authors: Hasan, Mahedi, Ashik, Arafat Islam, Chowdhury, Md Belal, Tasnim, Atiya Tahira, Nishat, Zakia Sultana, Hossain, Tanvir, Ahmed, Shamim
Formato: Artigo
Idioma:Inglês
Publicado em: The Author(s). Published by Elsevier Ltd. 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028608/
https://ncbi.nlm.nih.gov/pubmed/33846694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imu.2021.100569
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