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Tumor and Systemic Immunomodulatory Effects of MEK Inhibition
PURPOSE OF REVIEW: Mitogen-activated protein kinase (MAPK) kinase (MEK) is an integral component of the RAS signaling pathway, one of the most frequently mutated pathways in cancer biology. MEK inhibitors were initially developed to directly target oncogenic signaling, but are recognized to have ple...
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| Опубликовано в: : | Curr Oncol Rep |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8028056/ https://ncbi.nlm.nih.gov/pubmed/33547983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-020-01008-4 |
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