Decreased striatal adenosine A(2A)-dopamine D(2) receptor heteromerization in schizophrenia

According to the adenosine hypothesis of schizophrenia, the classically associated hyperdopaminergic state may be secondary to a loss of function of the adenosinergic system. Such a hypoadenosinergic state might either be due to a reduction of the extracellular levels of adenosine or alterations in...

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Publicat a:Neuropsychopharmacology
Autors principals: Valle-León, Marta, Callado, Luis F., Aso, Ester, Cajiao-Manrique, María M., Sahlholm, Kristoffer, López-Cano, Marc, Soler, Concepció, Altafaj, Xavier, Watanabe, Masahiko, Ferré, Sergi, Fernández-Dueñas, Víctor, Menchón, José M., Ciruela, Francisco
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027896/
https://ncbi.nlm.nih.gov/pubmed/33010795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-00872-9
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