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Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism

In patients with sepsis, lipopolysaccharide (LPS) from the outer membrane of gram-negative bacteria triggers cardiac dysfunction and heart failure, but target therapy for septic cardiomyopathy remains unavailable. In this study we evaluated the beneficial effects of cardamonin (CAR), a flavone exist...

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Publicado en:Acta Pharmacol Sin
Autores principales: Tan, Ying, Wan, Hong-hong, Sun, Ming-ming, Zhang, Wen-jing, Dong, Maolong, Ge, Wei, Ren, Jun, Peng, Hu
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Singapore 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027872/
https://ncbi.nlm.nih.gov/pubmed/32317756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0397-3
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