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Ubiquitin–proteasome system-targeted therapy for uveal melanoma: what is the evidence?
Uveal melanoma (UM) is a rare ocular tumor. The loss of BRCA1-associated protein 1 (BAP1) and the aberrant activation of G protein subunit alpha q (GNAQ)/G protein subunit alpha 11 (GNA11) contribute to the frequent metastasis of UM. Thus far, limited molecular-targeted therapies have been developed...
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| Veröffentlicht in: | Acta Pharmacol Sin |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Singapore
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8027653/ https://ncbi.nlm.nih.gov/pubmed/32601365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0441-3 |
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