Ubiquitin–proteasome system-targeted therapy for uveal melanoma: what is the evidence?

Uveal melanoma (UM) is a rare ocular tumor. The loss of BRCA1-associated protein 1 (BAP1) and the aberrant activation of G protein subunit alpha q (GNAQ)/G protein subunit alpha 11 (GNA11) contribute to the frequent metastasis of UM. Thus far, limited molecular-targeted therapies have been developed...

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Detaylı Bibliyografya
Yayımlandı:Acta Pharmacol Sin
Asıl Yazarlar: Zhao, Chen-xi, Zeng, Chen-ming, Wang, Ke, He, Qiao-jun, Yang, Bo, Zhou, Fan-fan, Zhu, Hong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Singapore 2020
Konular:
Review Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027653/
https://ncbi.nlm.nih.gov/pubmed/32601365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0441-3
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