Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

How the innate and adaptive host immune system miscommunicate to worsen COVID-19 immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune profiling of bronchoalveolar lavage (BAL) samples from 5 patients with mild and 26 with critical COVID-19 in comparison to BALs fro...

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Veröffentlicht in:Cell Res
Hauptverfasser: Wauters, Els, Van Mol, Pierre, Garg, Abhishek Dinkarnath, Jansen, Sander, Van Herck, Yannick, Vanderbeke, Lore, Bassez, Ayse, Boeckx, Bram, Malengier-Devlies, Bert, Timmerman, Anna, Van Brussel, Thomas, Van Buyten, Tina, Schepers, Rogier, Heylen, Elisabeth, Dauwe, Dieter, Dooms, Christophe, Gunst, Jan, Hermans, Greet, Meersseman, Philippe, Testelmans, Dries, Yserbyt, Jonas, Tejpar, Sabine, De Wever, Walter, Matthys, Patrick, Neyts, Johan, Wauters, Joost, Qian, Junbin, Lambrechts, Diether
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Nature Singapore 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027624/
https://ncbi.nlm.nih.gov/pubmed/33473155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-00455-9
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