Leaky Gut Driven by Dysbiosis Augments Activation and Accumulation of Liver Macrophages via RIP3 Signaling Pathway in Autoimmune Hepatitis

The gut–liver axis has been increasingly recognized as a major autoimmunity modulator. However, the implications of intestinal barrier in the pathogenesis of autoimmune hepatitis (AIH) remain elusive. Here, we investigated the functional role of gut barrier and intestinal microbiota for hepatic inna...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhang, Hongxia, Liu, Man, Zhong, Weilong, Zheng, Yanping, Li, Yanni, Guo, Liping, Zhang, Yujie, Ran, Ying, Zhao, Jingwen, Zhou, Lu, Wang, Bangmao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027109/
https://ncbi.nlm.nih.gov/pubmed/33841405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.624360
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