Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool

Signaling via interleukin-2 receptor (IL-2R) is a requisite for regulatory T (Treg) cell identity and function. However, it is not completely understood to what degree IL-2R signaling is required for Treg cell homeostasis, lineage stability and function in both resting and inflammatory conditions. H...

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Détails bibliographiques
Publié dans:Cell Mol Immunol
Auteurs principaux: Permanyer, Marc, Bošnjak, Berislav, Glage, Silke, Friedrichsen, Michaela, Floess, Stefan, Huehn, Jochen, Patzer, Gwendolyn E., Odak, Ivan, Eckert, Nadine, Zargari, Razieh, Ospina-Quintero, Laura, Georgiev, Hristo, Förster, Reinhold
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027001/
https://ncbi.nlm.nih.gov/pubmed/33408345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-00599-z
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