Consistency of the S5 DNA methylation classifier in formalin‐fixed biopsies versus corresponding exfoliated cells for the detection of pre‐cancerous cervical lesions

Methylation biomarkers are promising tools for diagnosis and disease prevention. The S5 classifier is aimed at the prevention of cervical cancer by the early detection of cervical intraepithelial neoplasia (CIN). S5 is based on pyrosequencing a promoter region of EPB41L3 and five late regions of HPV...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Reuter, Caroline, Preece, Matthew, Banwait, Rawinder, Boer, Sabrina, Cuzick, Jack, Lorincz, Attila, Nedjai, Belinda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026949/
https://ncbi.nlm.nih.gov/pubmed/33710792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3849
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