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MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy

MX2 is an interferon inducible gene that is mostly known for its antiviral activity. We have previously demonstrated that MX2 is also associated with the tumorigenesis process in melanoma. However, it remains unknown which molecular mechanisms are regulated by MX2 in response to interferon signaling...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Juraleviciute, Marina, Nsengimana, Jérémie, Newton‐Bishop, Julia, Hendriks, Gert J., Slipicevic, Ana
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026919/
https://ncbi.nlm.nih.gov/pubmed/33734579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3846
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