Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records

BACKGROUND: Clostridioides difficile is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to Clostridioides difficile infection has not been studied on a large-scale. METHODS: A total of 1,160 Clostridioides difficile infection cases and 15,304 contr...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Li, Jiang, Zhang, Yanfei, Jilg, Alexandria L., Wolk, Donna M., Khara, Harshit S., Kolinovsky, Amy, Rolston, David D. K., Hontecillas, Raquel, Bassaganya-Riera, Josep, Williams, Marc S., Abedi, Vida, Lee, Ming Ta Michael
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026859/
https://ncbi.nlm.nih.gov/pubmed/33841421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638913
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