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Distinct effects of pharmacological inhibition of stromelysin1 on endothelial-to-mesenchymal transition and myofibroblast differentiation

Endothelial-to-mesenchymal transition (EndMT) and fibroblast-to-myofibroblast (FibroMF) differentiation are frequently reported in organ fibrosis. Stromelysin1, a matrix metalloprotease-3 (MMP3) has been indicated in vascular pathologies and organ injuries that often lead to fibrosis. In the current...

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Bibliografske podrobnosti
izdano v:J Cell Physiol
Main Authors: Alharthi, Ahlam, Verma, Arti, Sabbineni, Harika, Adil, Mir S., Somanath, Payaningal R.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026649/
https://ncbi.nlm.nih.gov/pubmed/33319933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.30221
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