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Single-cell Analysis of the Developing Human Testis Reveals Somatic Niche Cell Specification and Fetal Germline Stem Cell Establishment

Human testis development in prenatal life involves complex changes in germline and somatic cell identity. To better understand, we profiled and analyzed ~32,500 single-cell transcriptomes of testicular cells from embryonic, fetal and infant stages. Our data shows that at 6-7 weeks post-fertilization...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Guo, Jingtao, Sosa, Enrique, Chitiashvili, Tsotne, Nie, Xichen, Rojas, Ernesto Javier, Oliver, Elizabeth, Connect, Donor, Plath, Kathrin, Hotaling, James M., Stukenborg, Jan-Bernd, Clark, Amander T., Cairns, Bradley R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026516/
https://ncbi.nlm.nih.gov/pubmed/33453151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.12.004
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