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Increased Hippocampal Excitability and Altered Learning Dynamics Mediate Cognitive Mapping Deficits in Human Aging

Learning the spatial layout of a novel environment is associated with dynamic activity changes in the hippocampus and in medial parietal areas. With advancing age, the ability to learn spatial environments deteriorates substantially but the underlying neural mechanisms are not well understood. Here,...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Diersch, Nadine, Valdes-Herrera, Jose P., Tempelmann, Claus, Wolbers, Thomas
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026345/
https://ncbi.nlm.nih.gov/pubmed/33648956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0528-20.2021
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