GABA transporter sustains IL-1β production in macrophages

Accumulating evidence shows that nervous system governs host immune responses; however, how γ-aminobutyric acid (GABA)ergic system shapes the function of innate immune cells is poorly defined. Here, we demonstrate that GABA transporter (GAT2) modulates the macrophage function. GAT2 deficiency lowers...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Xia, Yaoyao, He, Fang, Wu, Xiaoyan, Tan, Bie, Chen, Siyuan, Liao, Yuexia, Qi, Ming, Chen, Shuai, Peng, Yuanyi, Yin, Yulong, Ren, Wenkai
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026138/
https://ncbi.nlm.nih.gov/pubmed/33827820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe9274
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