Phospholipase A(2) inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression

Treating osteoarthritis (OA) remains a major clinical challenge. Despite recent advances in drug discovery and development, no disease-modifying drug for knee OA has emerged with any notable clinical success, in part, due to the lack of valid and responsive therapeutic targets and poor drug delivery...

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Pubblicato in:Sci Adv
Autori principali: Wei, Yulong, Yan, Lesan, Luo, Lijun, Gui, Tao, Jang, Biang, Amirshaghaghi, Ahmad, You, Tianyan, Tsourkas, Andrew, Qin, Ling, Cheng, Zhiliang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2021
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026133/
https://ncbi.nlm.nih.gov/pubmed/33827816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe6374
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