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Fingerprinting Bacterial Metabolic Response to Erythromycin by Raman-Integrated Mid-Infrared Photothermal Microscopy

We report rapid and sensitive phenotyping of bacterial response to antibiotic treatment at single-cell resolution by a Raman-integrated optical mid-infrared photothermal (MIP) microscope. The MIP microscope successfully detected biochemical changes of bacteria in specific to the acting mechanism of...

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Xu, Jiabao, Li, Xiaojie, Guo, Zhongyue, Huang, Wei E., Cheng, Ji-Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025921/
https://ncbi.nlm.nih.gov/pubmed/33089997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c02489
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