Crystal structures of β-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies

The canonical O-mannosylation pathway in humans is essential for the functional glycosylation of α-dystroglycan. Disruption of this post-translational modification pathway leads to congenital muscular dystrophies. The first committed step in the construction of a functional matriglycan structure inv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Crystallogr D Struct Biol
Egile Nagusiak: Yang, Jeong Yeh, Halmo, Stephanie M., Praissman, Jeremy, Chapla, Digantkumar, Singh, Danish, Wells, Lance, Moremen, Kelley W., Lanzilotta, William N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2021
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025878/
https://ncbi.nlm.nih.gov/pubmed/33825709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798321001261
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