Targeted Intravenous Nanoparticle Delivery: Role of Flow and Endothelial Glycocalyx Integrity

Therapies for atherosclerotic cardiovascular disease should target early disease stages and specific vascular sites where disease occurs. Endothelial glycocalyx (GCX) degradation compromises endothelial barrier function and increases vascular permeability. This initiates pro-atherosclerotic lipids a...

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Bibliografiske detaljer
Udgivet i:Ann Biomed Eng
Main Authors: Cheng, Ming J., Mitra, Ronodeep, Okorafor, Chinedu C., Nersesyan, Alina A., Harding, Ian C., Bal, Nandita N., Kumar, Rajiv, Jo, Hanjoong, Sridhar, Srinivas, Ebong, Eno E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025840/
https://ncbi.nlm.nih.gov/pubmed/32072383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-020-02474-4
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