Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom

We evaluated the safety, optimal dose, and preliminary effectiveness of a new-approach Africanized honeybee (Apis mellifera) Antivenom (AAV) in a phase I/II, multicenter, non-randomized, single-arm clinical trial involving 20 participants with multiple stings. Participants received 2 to 10 vials of...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Barbosa, Alexandre Naime, Ferreira, Rui Seabra, de Carvalho, Francilene Capel Tavares, Schuelter-Trevisol, Fabiana, Mendes, Mônica Bannwart, Mendonça, Bruna Cavecci, Batista, José Nixon, Trevisol, Daisson José, Boyer, Leslie, Chippaux, Jean-Philippe, Medolago, Natália Bronzatto, Cassaro, Claudia Vilalva, Carneiro, Márcia Tonin Rigotto, de Oliveira, Ana Paola Piloto, Pimenta, Daniel Carvalho, da Cunha, Luís Eduardo Ribeiro, dos Santos, Lucilene Delazari, Barraviera, Benedito
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025786/
https://ncbi.nlm.nih.gov/pubmed/33841437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.653151
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