Hepatic deficiency of augmenter of liver regeneration predisposes to nonalcoholic steatohepatitis and fibrosis

The augmenter of liver regeneration protein (ALR) is critical for lipid homeostasis and mitochondrial function. We investigated high fat/high carbohydrate diet (HF/HC)-induced nonalcoholic fatty liver disease (NAFLD) in wild-type, and hepatocyte-specific ALR-knockout (ALR-H-KO) and ALR-heterozygous...

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Publicado no:Hepatology
Main Authors: Kumar, Sudhir, Verma, Alok K., Rani, Richa, Sharma, Akanksha, Wang, Jiang, Shah, Shimul A., Behari, Jaideep, Gonzalez, Rosa Salazar, Kohli, Rohit, Gandhi, Chandrashekhar R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025692/
https://ncbi.nlm.nih.gov/pubmed/32031683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31167
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