Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina

BACKGROUND: Adult mesenchymal stem cells (MSCs) have been studied extensively for regenerative medicine; however, they have limited proliferation in vitro, and the long culture time induces cell senescence. MSCs also contribute to tissue repair through their paracrine function. In this study, we sou...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Zhuang, Guobing, Wen, Yan, Briggs, Mason, Shao, Qingchun, Tran, Darlene, Wang, Hongbo, Chen, Bertha
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025391/
https://ncbi.nlm.nih.gov/pubmed/33823931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02292-y
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