Persistent variations of blood DNA methylation associated with treatment exposures and risk for cardiometabolic outcomes in long-term survivors of childhood cancer in the St. Jude Lifetime Cohort

BACKGROUND: It is well-established that cancer treatment substantially increases the risk of long-term adverse health outcomes among childhood cancer survivors. However, there is limited research on the underlying mechanisms. To elucidate the pathophysiology and a possible causal pathway from treatm...

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Vydáno v:Genome Med
Hlavní autoři: Song, Nan, Hsu, Chia-Wei, Pan, Haitao, Zheng, Yinan, Hou, Lifang, Sim, Jin-ah, Li, Zhenghong, Mulder, Heather, Easton, John, Walker, Emily, Neale, Geoffrey, Wilson, Carmen L., Ness, Kirsten K., Krull, Kevin R., Srivastava, Deo Kumar, Yasui, Yutaka, Zhang, Jinghui, Hudson, Melissa M., Robison, Leslie L., Huang, I-Chan, Wang, Zhaoming
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025387/
https://ncbi.nlm.nih.gov/pubmed/33823916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00875-1
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