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The dark side of histones: genomic organization and role of oncohistones in cancer

BACKGROUND: The oncogenic role of histone mutations is one of the most relevant discovery in cancer epigenetics. Recurrent mutations targeting histone genes have been described in pediatric brain tumors, chondroblastoma, giant cell tumor of bone and other tumor types. The demonstration that mutant h...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Amatori, Stefano, Tavolaro, Simona, Gambardella, Stefano, Fanelli, Mirco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025322/
https://ncbi.nlm.nih.gov/pubmed/33827674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01057-x
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