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A novel 3D polycaprolactone high-throughput system for evaluation of toxicity in normoxia and hypoxia

Two-dimensional (2D) culturing of cancer cells has been indispensable for the development of anti-cancer drugs. Drug development, however, is lengthy and costly with a high attrition rate, calling to mind that 2D culturing does not mimic the three-dimensional (3D) tumour microenvironment in vivo. Th...

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Publicat a:Toxicol Rep
Autors principals: Malakpour-Permlid, Atena, Oredsson, Stina
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024882/
https://ncbi.nlm.nih.gov/pubmed/33854950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2021.03.015
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