Pan-cancer noncoding genomic analysis identifies functional CDC20 promoter mutation hotspots

Noncoding DNA sequences occupy more than 98% of the human genome; however, few cancer noncoding drivers have been identified compared with cancer coding drivers, probably because cancer noncoding drivers have a distinct mutation pattern due to the distinct function of noncoding DNA. Here we performe...

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Publicado no:iScience
Main Authors: He, Zaoke, Wu, Tao, Wang, Shixiang, Zhang, Jing, Sun, Xiaoqin, Tao, Ziyu, Zhao, Xiangyu, Li, Huimin, Wu, Kai, Liu, Xue-Song
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024666/
https://ncbi.nlm.nih.gov/pubmed/33851100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102285
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