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Of Lymph Nodes and CLL Cells: Deciphering the Role of CCR7 in the Pathogenesis of CLL and Understanding Its Potential as Therapeutic Target

The lymph node (LN) is an essential tissue for achieving effective immune responses but it is also critical in the pathogenesis of chronic lymphocytic leukemia (CLL). Within the multitude of signaling pathways aberrantly regulated in CLL the homeostatic axis composed by the chemokine receptor CCR7 a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cuesta-Mateos, Carlos, Brown, Jennifer R., Terrón, Fernando, Muñoz-Calleja, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024566/
https://ncbi.nlm.nih.gov/pubmed/33841445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.662866
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