Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen

Malaria transmission-blocking vaccines (TBVs) prevent the completion of the developmental lifecycle of malarial parasites within the mosquito vector, effectively blocking subsequent infections. The mosquito midgut protein Anopheline alanyl aminopeptidase N (AnAPN1) is the leading, mosquito-based TBV...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Bender, Nicole G., Khare, Prachi, Martinez, Juan, Tweedell, Rebecca E., Nyasembe, Vincent O., López-Gutiérrez, Borja, Tripathi, Abhai, Miller, Dustin, Hamerly, Timothy, Vela, Eric M., Davis, Ryan R., Howard, Randall F., Nsango, Sandrine, Cobb, Ronald R., Harbers, Matthias, Dinglasan, Rhoel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024329/
https://ncbi.nlm.nih.gov/pubmed/33824336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00309-4
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