Lysine-specific demethylase 1 inhibition enhances autophagy and attenuates early-stage post-spinal cord injury apoptosis

Neuron death in spinal cords is caused primarily by apoptosis after spinal cord injury (SCI). Autophagy can act as a cellular response to maintain neuron homeostasis that can reduce apoptosis. Although more studies have shown that an epigenetic enzyme called Lysine-specific demethylase 1 (LSD1) can...

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Опубликовано в: :Cell Death Discov
Главные авторы: Gu, Yang, Chen, Dehui, Zhou, Linquan, Zhao, Xin, Lin, Jiemin, Lin, Bin, Lin, Taotao, Chen, Zhi, Chen, Zhaohong, Wang, Zhenyu, Liu, Wenge
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024310/
https://ncbi.nlm.nih.gov/pubmed/33824301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00455-7
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