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Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury

The toll-like receptor 5 (TLR5) agonist, CBLB502/Entolimod, is a peptide derived from bacterial flagellin and has been shown to protect against radiation-induced tissue damage in animal models. Here we investigated the protective mechanism of CBLB502 in the liver using models of ischemia-reperfusion...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Melin, Nicolas, Sánchez-Taltavull, Daniel, Fahrner, René, Keogh, Adrian, Dosch, Michel, Büchi, Isabel, Zimmer, Yitzhak, Medová, Michaela, Beldi, Guido, Aebersold, Daniel M., Candinas, Daniel, Stroka, Deborah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024273/
https://ncbi.nlm.nih.gov/pubmed/33824326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03654-3
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