Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial

BACKGROUND: Glucocorticoids are among the most commonly prescribed drugs, but there is no biomarker that can quantify their action. The aim of the study was to identify and validate circulating biomarkers of glucocorticoid action. METHODS: In a randomized, crossover, single-blind, discovery study, 1...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Chantzichristos, Dimitrios, Svensson, Per-Arne, Garner, Terence, Glad, Camilla AM, Walker, Brian R, Bergthorsdottir, Ragnhildur, Ragnarsson, Oskar, Trimpou, Penelope, Stimson, Roland H, Borresen, Stina W, Feldt-Rasmussen, Ulla, Jansson, Per-Anders, Skrtic, Stanko, Stevens, Adam, Johannsson, Gudmundur
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Computational and Systems Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024021/
https://ncbi.nlm.nih.gov/pubmed/33821793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62236
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