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Revisiting the genome-wide significance threshold for common variant GWAS
Over the last decade, GWAS meta-analyses have used a strict P-value threshold of 5 × 10(−8) to classify associations as significant. Here, we use our current understanding of frequently studied traits including lipid levels, height, and BMI to revisit this genome-wide significance threshold. We comp...
Shranjeno v:
| izdano v: | G3 (Bethesda) |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8022962/ https://ncbi.nlm.nih.gov/pubmed/33585870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/g3journal/jkaa056 |
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